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If something goes against the grain, you would not usually do it because it would be unusual.
不正常，违反常理;与…格格不入
grain /greɪn/
n. 谷粒, 谷物, 谷类
小的硬粒
(天然)纹理
These days it goes against the grain to show too much respect for authority.
如今尊重权威反而不正常了。