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v./ˈhæn.dəl/
to deal with, have responsibility for, or be in charge of
处理，应付，负责
I thought he handled the situation very well.
我认为他把局面处理得非常好。
Some people are brilliant with computers, but have no idea how to handle (= behave with) other people.
有些人在计算机方面很出色，却不会与人打交道。