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压力存在于大脑的哪个部位?科学家们也许知道答案

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2020年05月29日

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Where does stress live in the brain? Scientists may have the answer

压力存在于大脑的哪个部位?科学家们也许知道答案

A new study from scientists at Yale University have found where stress lives in the brain.

耶鲁大学科学家的一项新研究发现了压力在大脑中的位置。

Higher levels of stress are found in the hypothalamus; lower stress are found in the dorsal lateral frontal cortex.

下丘脑的压力水平较高,背侧额叶皮层的压力水平较低。

压力存在于大脑的哪个部位?科学家们也许知道答案

Test subjects were given fMRI scans while looking at images of distress including a snarling dog, mutilated faces, or filthy toilets.

受试者在观看包括咆哮的狗、残缺不全的脸或脏兮兮的厕所在内的痛苦图像时接受功能磁共振成像扫描。

"Despite the distinct roles of these networks, our findings suggest that individuals engaged both positive and negative networks adaptively to attenuate feelings of stress," the Yale scientists explain in their study.

耶鲁大学的科学家在他们的研究中解释说:“尽管这些网络有着不同的作用,但我们的研究结果表明,个体可以适应地利用积极和消极的网络来减轻压力感。”。

"That is, participants had higher connectivity with negative networks, but, at the same time, had lower connectivity with positive networks."

也就是说,参与者与消极网络的连接度较高,但同时与积极网络的连接度较低

The world currently is suffering from widespread psychological distress from the immediate health aspects of the global coronavirus pandemic, the consequences of physical isolation, fear of infection, dying and losing family members, physical distancing from loved ones and peers, and economic turmoil.

目前,世界正因全球冠状病毒大流行的直接健康问题、身体隔离的后果、对感染的恐惧、家庭成员的死亡和失去、与亲人和同龄人的身体疏远以及经济动荡而遭受广泛的心理痛苦。

Those most at risk and in need of help are frontline health care workers, older people, adolescents, young people, those with preexisting mental health conditions, and those caught up in conflict and crisis.

最危险和最需要帮助的是第一线的卫生保健工作者、老年人、青少年、年轻人、有精神健康问题的人以及陷入冲突和危机的人。

压力存在于大脑的哪个部位?科学家们也许知道答案

A 17-page United Nations briefing pointed to a historic under-investment in mental health needs and called for the widespread availability of emergency mental health and psychological support during the pandemic.

一份长达17页的联合国简报指出,对精神卫生需求的投资历来不足,并呼吁在大流行期间广泛提供紧急精神卫生和心理支持。

“These findings may help us tailor a therapeutic intervention to multiple targets, such as increasing the strength of the connections from the hippocampus to the frontal cortex or decreasing the signaling to the physiological stress centers,” Rajita Sinha, the Foundations Fund professor of psychiatry and a professor in Yale’s Child Study Center and neuroscience department, told Yale News.

拉吉塔·辛哈说:“这些发现可能有助于我们针对多个目标制定治疗干预措施,例如增加海马体与额叶皮质之间的连接强度,或减少与生理应激中心的信号传导。”基金会的精神病学教授、耶鲁儿童研究中心和神经科学系的一位教授告诉耶鲁新闻。


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