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BBC News: 慢性睡眠不足如何增加患心脏病的风险





How chronic sleep loss can increase the risk of heart disease

Cutting sleep short on a regular basis may harm immune stem cells, potentially increasing the risk of inflammatory disorders and heart disease, a small new study suggests.
An analysis of blood samples from 14 healthy volunteers who agreed to have their sleep shortened by 1½ hours each night for six weeks revealed long-term changes in the way these stem cells behaved, leading to a proliferation of the white blood cells that can spark inflammation, according to the report published in the Journal of Experimental Medicine.
“The key message from this study is that sleep lessens inflammation and loss of sleep increases inflammation,” said study co-author Filip Swirski, the director of the Cardiovascular Research Institute at Icahn Mount Sinai in New York.
While a certain amount of inflammation is needed to fight infections and heal wounds, too much can be harmful, he explained.
Overabundant, persistent inflammation has been linked to heart disease and neurodegenerative diseases, like Alzheimer’s, he added.
“The real key is there are things we can do through our lifestyles — getting enough sleep, managing stress, getting enough exercise, consuming a healthy diet — that can reduce the speed of biological aging,” Swirski said. “We may not live forever, but we may live well into old age maintaining the quality of our lives by paying attention to some of these lifestyle factors.”.

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