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新奇事件簿 科学家发现抑郁分子

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2022年06月24日

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Scientists say they have discovered the part of the brain that is responsible for us feeling miserable, anxious and stressed. A UK-based medical research company called Heptares Therapeutics said it has located the molecule related to depression. It is a protein found inside the brain called CRF1. The company said the protein, "is important in regulating the body's response to stress and is implicated in stress-related diseases such as depression and anxiety". The team used one of the world's most powerful x-ray machines in its research. Lead researcher Fiona Marshall said a greater understanding of the CRF1 protein could lead to ground-breaking drugs to control depression.

科学家表示,他们发现了大脑中负责让我们感到痛苦,焦虑和压力的部分。位于英国的一家名叫Heptares Therapeutics的医疗研究公司表示,他们确定了与抑郁有关的分子的位置,大脑内部一种叫作CRF1的蛋白质。这家公司表示,这种蛋白质“对于调控身体对压力的反应非常重要,与压力有关的疾病有密切关联,比如抑郁和焦虑。”该小组在研究中使用了世界上最强大的X射线仪。首席研究人员Fiona Marshall表示,对CRF1蛋白质更好的了解能够促进研发出控制抑郁的突破性药物。

Britain's National Health Service (NHS) warned anyone suffering from depression or related illnesses not to get too excited about this research. It questioned whether a single molecule could really lead to depression, and said the condition actually resulted from a complex interaction of chemicals. An NHS statement expressed surprise at the way two of Britain's biggest newspapers have built the story up – "The Daily Mail" and "The Sunday Times". The latter reported that researchers had found the "miserable molecule," saying it was "the protein involved in all our feelings of stress, anxiety and even depression". The NHS said: "It's a great headline, but a hugely sweeping claim."

英国国民健康服务系统(NHS)警告任何患有抑郁症或相关疾病的人都不要对这份研究过分激动。该机构质疑单一的分子是否能够造成抑郁。他们认为抑郁症实际上是由于各种化学物质的相互作用。NHS一份声明对英国两家最大的报社宣扬该研究的方式感到惊讶,分别是《每日邮报》和《星期日泰晤士报》。后者报道称,研究人员发现了“痛苦分子”,称这是“关系到我们所有压力,焦虑甚至抑郁情绪的蛋白质”。NHS表示:“这是个很吸引人的标题,但是太夸大其词了。”

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