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《考研英语阅读理解100篇 基础版》第7章 医药类 Unit 85

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2019年01月23日

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Shortages of flu vaccine are nothing new in America,but this year's is a whopper.Until last week,it appeared that 100 million Americans would have access to flu shots this fall.Then British authorities,concerned about quality-control problems at a production plant in Liverpool,barred all further shipments by the Chiron Corp.Overnight,the U.S.vaccine supply dwindled by nearly half—and federal health officials found themselves making an unusual plea.Instead of beseeching us all to get vaccinated,they’re now urging most healthy people between the ages of 2 and 64 not to.“This re-emphasizes the fragility of our vaccine supply,” says Dr.Martin Myers of the National Network for Immunization Information,“and the lack of redundancy in our system.” 
Why is such a basic health service so easily knocked out? Mainly because private companies have had little incentive to pursue it.To create a single dose of flu vaccine,a manufacturer has to grow live virus in a 2-week-old fertilized chicken egg,then crack the egg,harvest the virus and extract the proteins used to provoke an immune response.Profit margins are narrow,demand is fickle and,because each year's flu virus is different,any leftover vaccine goes to waste.As a result,the United States now has only two major suppliers (Chiron and Aventis Pasteur)—and when one of them runs into trouble,there isn’t much the other can do about it.“A vaccine maker can’t just call up and order 40 million more fertilized eggs,” says Manon Cox,of Connecticut-based Protein Sciences Corp.“There's a whole industry that's scheduled to produce a certain number of eggs at a certain time.” 
Sleeker technologies are now in the works,and experts are hoping that this year's fiasco will speed the pace of innovation.The main challenge is to shift production from eggs into cell cultures—a medium already used to make most other vaccines.Flu vaccines are harder than most to produce this way,but several biotech companies are now pursuing this strategy,and one culture-based product(Solvay Pharmaceuticals’ Invivac)has been cleared for marketing in Europe. 
For America,the immediate challenge is to make the most of a limited supply.The government estimates that 95 million people still qualify for shots under the voluntary restrictions announced last week.That's nearly twice the number of doses that clinics will have on hand,but only 60 million Americans seek out shots in a normal year.In fact,many experts are hoping the shortage will serve as an awareness campaign—encouraging the people who really need a flu shot to get one. 
注(1):本文选自Newsweek; 
注(2):本文习题命题模仿对象:第1~4题分别模仿1997年真题Text 3第1~4题,第5题模仿1997年真题Text 4第4题。 
1.Shortages of flue vaccine show that ______. 
A) America relies too much on foreign suppliers 
B) the demand of flue vaccines is high this year 
C) quality problem is a serious problem in flu vaccine production 
D) the supply of flu vaccines is rather weak and America has no back-up measures to make it up 
2.The word“cleared” (Line 5,Paragraph 3)might mean ______. 
A) permitted 
B) removed 
C) proved 
D) produced 
3.Private companies have little interest in producing flu vaccines because of ______. 
A) complicated process,high cost,low profit and high risk 
B) shortages of fertilized chicken eggs 
C) difficulty in growing live virus 
D) fast changing of flu virus 
4.From the last paragraph we can infer that ______. 
A) the government hopes to solve the problem by way of volunteer restrictions 
B) more than 47 million Americans who are qualified to get flu vaccine shots cannot get them this year 
C) America needs not to worry about a limited supply of flu vaccines this year 
D) normally only a small percentage of American population gets flu vaccine shots each year 
5.According to the passage,which of the following is TRUE? 
A) All Americans are persuaded not to get vaccinated this year. 
B) The big problem in innovating flu vaccine's producing technique is how to grow virus in a new way. 
C) More flu vaccines cannot be produced in a short time because private companies refuse to produce more. 
D) Flu vaccines are easier than most vaccines to produce through cell cultures. 

流感疫苗短缺在美国不足为奇,但今年的短缺传闻却是一个弥天大谎。到上周为止,好像还有1亿美国人能在今年秋季接种流感疫苗。紧接着,英国当局因为担心一家位于利物浦的生产厂的质量控制问题而禁止所有Chiron Corp公司的产品供应。一夜之间,美国的疫苗供应量减少了近一半——而联邦卫生官员也发现他们正在提出一项不同寻常的请求:不是请求我们去注射疫苗,而是敦促那些年龄在2~64岁之间的绝大多数健康人不去注射疫苗。“这再次凸显出我们疫苗供应的脆弱性,”全国免疫信息网的马丁·迈尔斯医生说,“此外,我们也没有必要的补救机制。” 
为什么这种基本的保健服务会如此不堪一击呢?主要原因是私人公司生产积极性不高。生产每一份流感疫苗,生产商都要在一枚受精两星期的鸡蛋中培育活病毒,然后打破鸡蛋,提取病毒和用来激发免疫反应的蛋白质。利润率低,需求不稳定,此外由于每年的流感病毒不同,剩余的疫苗只能报废。因此美国目前只有两家大的供应商(Chiron Corp和Aventis Pasteur)——当其中一家公司遇到麻烦时,另一家公司也无能为力。“疫苗生产商根本不可能打个电话多要4000万个受精鸡蛋,”在康涅狄格一家蛋白质科学公司工作的马农·考克斯说,“整个鸡蛋生产都是按计划进行的。什么时间生产多少鸡蛋都是已经预先计划好的。” 
目前的生产已经采用更好的技术。专家们希望今年的教训能够加快技术革新的步伐。最大的挑战是如何将疫苗生产从鸡蛋培育转向细胞培育——该技术已经广泛应用于其他大部分疫苗的生产。用细胞培育技术生产流感疫苗比生产其他大部分疫苗难度更大。尽管如此,几家生物技术公司正在进行这方面的尝试。索马尔Invivac医药公司研制的一种基于细菌培育技术的产品已经获准在欧洲销售。 
对美国来说,当务之急是要利用好有限的流感疫苗。政府预计,尽管上周发布了自愿限制公告,仍有9500万人有资格注射疫苗。这个数字几乎是医院临床流感疫苗库存量的两倍。但正常情况下,每年仅有6000万美国人接种流感疫苗。事实上,许多专家希望这次疫苗短缺问题能成为一次提高公民道德意识的活动——鼓励那些确实需要注射疫苗的人们去注射。 
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