In 1953, James Watson and Francis Crick discovered the double helix structure of DNA, opening up endless possibilities for exploring the genome and genetics. For over 70 years, biologists around the world have ceaselessly researched DNA, attempting to unravel the mysteries of life at the microscopic level.
1953年,詹姆斯·沃森和弗朗西斯·克里克发现了DNA的双螺旋结构,为探索基因组和遗传学开辟了无限的可能性。 70多年来,世界各地的生物学家不断研究DNA,试图从微观层面揭开生命的奥秘。
Professor Zhai Yuanliang from the School of Biological Sciences at the University of Hong Kong is one of them. At age 45, he has devoted nearly half of his life to studying the molecular mechanisms of DNA replication.
香港大学生物科学学院的翟元良教授就是其中之一。 45岁的他将一生的近一半时间投入到研究DNA复制的分子机制上。
On Jan 5 last year, Zhai and his collaborators revealed a mechanism for the regulation of DNA replication by MCM(minichromosome maintenance) proteins in the top international scientific journal Cell. This research was selected as one of the top 10 scientific advancements in China last year, and Zhai's team was the only Hong Kong-based research team included on the list.
去年1月5日,翟和他的合作者在国际顶级科学杂志《细胞》上揭示了MCM(微型染色体维持)蛋白调控DNA复制的机制。 这项研究去年被评选为中国十大科学进展之一,而翟教授的团队是唯一入围的香港研究团队。
On March 6, Zhai and his team published their latest findings in Nature. It was the first time internationally that high-resolution details of the recycling process of parental histones within the framework of DNA replication had been demonstrated.
3月6日,翟教授及其团队在《Nature》杂志上发表了最新发现。 这是国际上首次展示 DNA 复制框架内亲本组蛋白回收过程的高分辨率细节。
"Today, our research capabilities in the field of DNA replication are at the forefront of the world," Zhai said.
“今天,我们在DNA复制领域的研究能力处于世界前列。”翟说。
When asked about what advancements he expects in the future, he said: "Now, with technological innovation, the threshold for structural biology is not as high as before. I look forward to more people being able to conduct the best scientific research, driving the progress of science and fostering the prosperous development of the entire scientific research ecosystem."
当被问及未来期望有哪些进步时,他说:“现在,随着技术的创新,结构生物学的门槛不再像以前那么高了。我期待更多的人能够进行最好的科学研究,推动结构生物学的发展。” 科学进步,促进整个科研生态系统的繁荣发展。”